Alaska had the highest chlamydia infection rates in the United States in 2010 and 2011, and has consistently had the first or second highest rate in the nation since 2000, according to the report.
The report also noted that despite being one of the highest rates in the nation this is a decrease of 5 percent from 2010 and the largest annual decrease ever recorded for Alaska.
Rates of infection declined everywhere in the state except the Gulf Coast region.
Chlamydia infections often coincide with gonorrhea infections.
Alaska saw an outbreak of gonorrhea in 2008 which peaked in 2010 and declined last year with 993 cases reported.
While Alaska still has rates higher than the national average, it was a 22 percent drop in cases between 2010 and 2011.
Both infections can result in pre-term labor, pelvic inflammatory disease, ectopic pregnancy and infertility in women and men among other problems.
The Department of Health and Social services recommends people at risk of sexually transmitted diseases use condoms correctly and consistently and limit the number of sexual partners.